• Stichting IWO wordt bestuurd door artsen die werkzaam zijn in verschillende organisaties en specialismen, maar hetzelfde doel voor ogen hebben

  • Stichting IWO wordt bestuurd door artsen die werkzaam zijn in verschillende organisaties en specialismen, maar hetzelfde doel voor ogen hebben

Nieuws

Eerste IWO-Webinar is groot succes!

Door de corona-crisis gedwongen, werd de IWO-avond in Utrecht van 22 april 2020 afgezegd. In de plaats daarvan werd er een webinar georganiseerd, met een opvallend hoog aantal deelnemers: in Utrecht meestal tussen 60 en 80 deelnemers, nu 132!

Het geheel werd gepresenteerd door de IWO bestuursleden Prof. Dr. Marielle Emmelot-Vonk en Prof. Dr. Willem F. Lems, vanuit de professionele studio van AV-Brothers uit Amersfoort. Klik hier voor de video van de webinar.

 

Volg hier relevant internationaal nieuws over osteoporose. De nieuwsfeed bevat zowel doorgeplaatste artikelen, als publicaties uit de Osteoporose journalen. Klik hier voor rss-feeds.

 

  • Prolonged 25-OH Vitamin D Deficiency Does Not Impair Bone Mineral Density in Adult Patients With Vitamin D 25-Hydroxylase Deficiency (CYP2R1).

    Calcif Tissue Int. 2020 May 19;: Authors: Wiedemann A, Renard E, Molin A, Weryha G, Oussalah A, Guéant JL, Feillet F Vitamin D-dependent rickets type 1B (VDDR1B) is an autosomal semidominant genetic disorder caused... Lees meer

    Gepost op 24 mei 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • History of alendronate.

    Bone. 2020 May 10;:115411 Authors: Cummings SR, Santora AC, Black DM, Russell RGG  Alendronate was synthesized in 1970s in a search for inhibitors of calcification. Istituto Gentili investigators identified it as a... Lees meer

    Gepost op 24 mei 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Radiology reporting of osteoporotic vertebral fragility fractures on computed tomography studies: results of a UK national audit.

    Eur Radiol. 2020 May 20;: Authors: Howlett DC, Drinkwater KJ, Mahmood N, Illes J, Griffin J, Javaid K OBJECTIVES: To evaluate organisational reporting infrastructure and patient-related reporting data in the diagnosis of... Lees meer

    Gepost op 24 mei 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Association Between Treatment With Apixaban, Dabigatran, Rivaroxaban, or Warfarin and Risk for Osteoporotic Fractures Among Patients With Atrial Fibrillation.

    Ann Intern Med. 2020 May 19;: Authors: Lau WCY, Cheung CL, Man KKC, Chan EW, Sing CW, Lip GYH, Siu CW, Lam JKY, Lee ACH, Wong ICK BACKGROUND: It is unclear whether anticoagulant type is associated with the risk for... Lees meer

    Gepost op 20 mei 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Can bone turnover markers help to define the suitability and duration of bisphosphonate drug holidays?

    Drugs Context. 2020;9: Authors: Statham L, Abdy S, Aspray TJ Background: On stopping bisphosphonate treatment, bone resorption may increase before evidence of a decrease in bone density. Offset of bisphosphonate effect... Lees meer

    Gepost op 20 mei 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Bisphosphonate drug holidays: Risk of fractures and mortality in a prospective cohort study.

    Bone. 2020 May 15;:115431 Authors: Pfeilschifter J, Steinebach I, Trampisch HJ, Rudolf H PURPOSE: This study examined osteoporotic fractures and mortality in patients pretreated with bisphosphonates (BPs) during BP... Lees meer

    Gepost op 19 mei 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Alendronate or Zoledronic acid do not impair wound healing after tooth extraction in postmenopausal women with osteoporosis.

    Bone. 2020 May 10;:115412 Authors: Lesclous P, Cloitre A, Catros S, Devoize L, Louvet B, Châtel C, Foissac F, Roux C BACKGROUND: Bisphosphonates (BPs) are widely used for the prevention or treatment of osteoporosis.... Lees meer

    Gepost op 17 mei 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Osteoporosis Management in the Era of COVID-19.

    J Bone Miner Res. 2020 May 14;: Authors: Yu EW, Tsourdi E, Clarke BL, Bauer DC, Drake MT Osteoporosis is a chronic condition which reflects reduced bone strength and an associated increased risk for fracture. As a chronic... Lees meer

    Gepost op 17 mei 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Characterization of fracture liaison service non-responders after invitation by home visits and questionnaires.

    Osteoporos Int. 2020 May 13;: Authors: van den Berg P, van Haard PMM, Geusens PP, van den Bergh JP, Schweitzer DH NTRODUCTION: The proportion of non-responding fracture liaison service (FLS) invitees is high but... Lees meer

    Gepost op 17 mei 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Endocrinology in the time of COVID-19: Management of calcium disorders and osteoporosis.

    Eur J Endocrinol. 2020 May 01;: Authors: Gittoes NJ, Criseno S, Appelman-Dijkstra NM, Bollerslev J, Canalis E, Rejnmark L, Hassan-Smith Z Endocrinologists have had to make rapid changes to services so that resources can... Lees meer

    Gepost op 15 mei 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Do patients that fracture with normal DXA-measured BMD have normal bone?

    Arch Osteoporos. 2020 May 11;15(1):70 Authors: Bandaru S, Hare K, Krueger D, Binkley N Patients that sustain "osteoporosis-related" fractures may have normal BMD at the hips and spine, but rarely have normal... Lees meer

    Gepost op 15 mei 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Bone densitometry worldwide: a global survey by the ISCD and IOF.

    Osteoporos Int. 2020 May 06;: Authors: Clynes MA, Westbury LD, Dennison EM, Kanis JA, Javaid MK, Harvey NC, Fujita M, Cooper C, Leslie WD, Shuhart CR, International Society for Clinical Densitometry (ISCD) and the... Lees meer

    Gepost op 12 mei 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • The relationship of 25-hydroxyvitamin D values and risk of fracture: a population-based retrospective cohort study.

    Osteoporos Int. 2020 May 06;: Authors: Aul AJ, Dudenkov DV, Mara KC, Juhn YJ, Wi CI, Maxson JA, Thacher TD INTRODUCTION: Studies of the relationship between serum 25-hydroxyvitamin D (25(OH)D) levels and fracture risk... Lees meer

    Gepost op 12 mei 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • History of risedronate.

    Bone. 2020 May 06;:115407 Authors: McClung MR, Ebetino FH Herein we review the discovery, development, commercial history and legacy of risedronate or NE-58095, a potent N-containing bisphosphonate developed by scientists... Lees meer

    Gepost op 12 mei 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Efficacy and safety of Romosozumab in treatment for low bone mineral density: a systematic review and meta-analysis.

    Clin Rheumatol. 2020 May 08;: Authors: Kaveh S, Hosseinifard H, Ghadimi N, Vojdanian M, Aryankhesal A Osteoporosis is a chronic skeletal disease with an increasing prevalence. Romosozumab, as a monoclonal anti-sclerostin... Lees meer

    Gepost op 12 mei 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Bisphosphonate utilization across the spectrum of eGFR.

    Arch Osteoporos. 2020 May 09;15(1):69 Authors: Titan SM, Laureati P, Sang Y, Chang AR, Evans M, Trevisan M, Levey AS, Grams ME, Inker LA, Carrero JJ INTRODUCTION: Osteoporosis is common in patients with chronic kidney... Lees meer

    Gepost op 12 mei 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Interventions to improve adherence to anti-osteoporosis medications: an updated systematic review.

    Osteoporos Int. 2020 May 01;: Authors: Cornelissen D, de Kunder S, Si L, Reginster JY, Evers S, Boonen A, Hiligsmann M, European Society for Clinical and Economic Aspect of Osteoporosis, Osteoarthritis and Musculoskeletal... Lees meer

    Gepost op 07 mei 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Duration of Bisphosphonate Drug Holidays and Associated Fracture Risk.

    Med Care. 2020 05;58(5):419-426 Authors: Curtis JR, Saag KG, Arora T, Wright NC, Yun H, Daigle S, Matthews R, Delzell E BACKGROUND: Discontinuation of bisphosphonates (BP) or a "drug holiday" after several years... Lees meer

    Gepost op 07 mei 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Targeted vertebral fracture assessment for optimizing fracture prevention in Canada.

    Arch Osteoporos. 2020 May 03;15(1):65 Authors: Leslie WD, Lix LM, Binkley N Vertebral fracture assessment (VFA) provides incremental information in identifying women and men aged 70 years and older qualifying for... Lees meer

    Gepost op 07 mei 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Once-yearly zoledronic acid and change in abdominal aortic calcification over 3 years in postmenopausal women with osteoporosis: results from the HORIZON Pivotal Fracture Trial.

    Osteoporos Int. 2020 May 02;: Authors: Cai G, Keen HI, Host LV, Aitken D, Laslett LL, Winzenberg T, Wluka AE, Black D, Jones G INTRODUCTION: Bisphosphonate use is associated with reduced risk of all-cause mortality and... Lees meer

    Gepost op 07 mei 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Adherence with brand versus generic bisphosphonates among osteoporosis patients: a new-user cohort study in the French National Healthcare Insurance database.

    Sci Rep. 2020 May 04;10(1):7446 Authors: Viprey M, Xue Y, Rousseau A, Payet C, Chapurlat R, Caillet P, Dima A, Schott AM Several studies documented declines in treatment adherence with generic forms of oral... Lees meer

    Gepost op 07 mei 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Clinical Characteristics of Familial Hypocalciuric Hypercalcaemia Type 1: A Multicentre Study of 77 Adult Patients.

    Clin Endocrinol (Oxf). 2020 Apr 29;: Authors: Mouly C, Vargas-Poussou R, Lienhardt A, Silve C, Hureaux M, Magdelaine C, Buffet A, Grunenwald S, Marc Kuhn J, Brue T, Reznik Y, Tabarin A, Martin-Coignard D, Haymann JP, Tack I,... Lees meer

    Gepost op 03 mei 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Osteoblast-Based Therapy-A New Approach for Bone Repair in Osteoporosis: Pre-Clinical Setting.

    Tissue Eng Regen Med. 2020 Apr 28;: Authors: Mahmoud NS, Mohamed MR, Ali MAM, Aglan HA, Amr KS, Ahmed HH BACKGROUND: Osteoporosis is a metabolic bone disease characterized by low bone density resulting in increased... Lees meer

    Gepost op 03 mei 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Osteoporosis in the age of COVID-19.

    Osteoporos Int. 2020 Apr 28;: Authors: Girgis CM, Clifton-Bligh RJ As the world grapples with the crisis of COVID-19, established economies and healthcare systems have been brought to their knees. Tough decisions... Lees meer

    Gepost op 03 mei 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Back pain from painful osteoporotic vertebral fractures: discrepancy between the actual fracture location and the location suggested by patient-reported pain or physical examination findings.

    Osteoporos Int. 2020 Apr 28;: Authors: Jin H, Ma X, Liu Y, Liu M, Yin X, Fan W, Zhu J, Zhao JH, Chen L, Su N, Xie Y, Yang J, Liu P INTRODUCTION: Whether the location of symptoms or physical examination findings delineates... Lees meer

    Gepost op 03 mei 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Zoledronate

    Bone. 2020 Apr 27;:115390 Authors: Reid IR, Green JR, Lyles KW, Reid DM, Trechsel U, Hosking DJ, Black DM, Cummings SR, Russell RGG, Eriksen EF oledronate is the most potent and most long-acting bisphosphonate in clinical... Lees meer

    Gepost op 03 mei 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • The association between renal function and BMD response to bisphosphonate treatment: Real-world cohort study using linked national registers.

    Bone. 2020 Apr 22;:115371 Authors: Abrahamsen B, Ernst MT, Smith CD, Nybo M, Rubin KH, Prieto-Alhambra D, Hermann AP BACKGROUND: Management of osteoporosis given reduced renal function is one of the largest challenges in... Lees meer

    Gepost op 28 april 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • 2019 EULAR points to consider for non-physician health professionals to prevent and manage fragility fractures in adults 50 years or older.

    Ann Rheum Dis. 2020 Apr 24;: Authors: Adams J, Wilson N, Hurkmans E, Bakkers M, Balážová P, Baxter M, Blavnsfeldt AB, Briot K, Chiari C, Cooper C, Dragoi RG, Gäbler G, Lems W, Mosor E, Pais S, Simon C,... Lees meer

    Gepost op 28 april 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Biomechanical Computed Tomography analysis (BCT) for clinical assessment of osteoporosis.

    Osteoporos Int. 2020 Apr 26;: Authors: Keaveny TM, Clarke BL, Cosman F, Orwoll ES, Siris ES, Khosla S, Bouxsein ML The surgeon general of the USA defines osteoporosis as "a skeletal disorder characterized by... Lees meer

    Gepost op 28 april 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Underevaluation of fractures by self-report: an analysis from the FRISBEE cohort.

    Arch Osteoporos. 2020 Apr 22;15(1):61 Authors: Baleanu F, Moreau M, Kinnard V, Iconaru L, Karmali R, Rozenberg S, Rubinstein M, Paesmans M, Bergmann P, Body JJon. I NTRODUCTION: Most fracture cohort studies rely on... Lees meer

    Gepost op 25 april 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Fragility fractures in Europe: burden, management and opportunities.

    Arch Osteoporos. 2020 Apr 19;15(1):59 Authors: Borgström F, Karlsson L, Ortsäter G, Norton N, Halbout P, Cooper C, Lorentzon M, McCloskey EV, Harvey NC, Javaid MK, Kanis JA, International Osteoporosis Foundation... Lees meer

    Gepost op 21 april 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Bone Mineral Densitometry Reporting: Pearls and Pitfalls.

    Can Assoc Radiol J. 2020 Apr 20;:846537120919627 Authors: Martineau P, Morgan SL, Leslie WD ] Dual-energy X-ray absorptiometry (DXA) is the method of choice for assessing bone mineral density (BMD). Unfortunately, the... Lees meer

    Gepost op 21 april 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Medications as a Risk Factor for Fragility Hip Fractures: A Systematic Review and Meta-analysis.

    Calcif Tissue Int. 2020 Apr 07;: Authors: Mortensen SJ, Mohamadi A, Wright CL, Chan JJ, Weaver MJ, von Keudell A, Nazarian A Fragility hip fractures and their associated morbidity and mortality pose a global healthcare... Lees meer

    Gepost op 10 april 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • 25-Hydroxyvitamin D and Risk of Osteoporotic Fractures: Mendelian Randomization Analysis in 2 Large Population-Based Cohorts.

    Clin Chem. 2020 Apr 07;: Authors: Çolak Y, Afzal S, Nordestgaard BG A BACKGROUND: Whether low plasma 25-hydroxyvitamin D concentrations cause osteoporotic fractures is unclear. We tested the hypothesis that low... Lees meer

    Gepost op 10 april 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Do patients with diabetes have an increased risk of impaired fracture healing? A systematic review and meta-analysis.

    ANZ J Surg. 2020 Apr 07;: Authors: Ding ZC, Zeng WN, Rong X, Liang ZM, Zhou ZK BACKGROUND: The majority of the existing evidence showing an association between diabetes and impaired fracture healing comes from basic... Lees meer

    Gepost op 10 april 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • A patient-level key performance indicator set to measure the effectiveness of fracture liaison services and guide quality improvement: a position paper of the IOF Capture the Fracture Working Group, National Osteoporosis Foundation and Fragility Fracture

    Osteoporos Int. 2020 Apr 08;: Authors: Javaid MK, Sami A, Lems W, Mitchell P, Thomas T, Singer A, Speerin R, Fujita M, Pierroz DD, Akesson K, Halbout P, Ferrari S, Cooper C INTRODUCTION: Fracture Liaison Services (FLSs)... Lees meer

    Gepost op 10 april 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Vertebral fracture assessment (VFA) in patients over 50 years of age with a non-severe peripheral fracture.

    Osteoporos Int. 2020 Apr 07;: Authors: Aboudiab M, Grados F, Batteux B, Henry-Desailly I, Fardellone P, Goëb V INTRODUCTION: The aim of this study was to evaluate the utility of VFA in detecting vertebral fractures... Lees meer

    Gepost op 10 april 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Effect of Tamoxifen on the Risk of Osteoporosis and Osteoporotic Fracture in Younger Breast Cancer Survivors: A Nationwide Study.

    Front Oncol. 2020;10:366 Authors: Lee J, Alqudaihi HM, Kang MS, Kim J, Lee JW, Ko BS, Son BH, Ahn SH, Lee JE, Han SW, Kim Z, Hur SM, Lee JS, Chung IY Background: Although international guidelines recommend bone screening... Lees meer

    Gepost op 10 april 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Estimation of Long-Term Efficacy of Denosumab Treatment in Postmenopausal Women With Osteoporosis: A FRAX- and Virtual Twin-Based Post Hoc Analysis From the FREEDOM and FREEDOM Extension Trials.

     JBMR Plus. 2020 Apr;4(4):e10348 Authors: Siris E, McDermott M, Pannacciulli N, Miller PD, Lewiecki EM, Chapurlat R, Jódar-Gimeno E, Huang S, Kanis JA   The 3-year placebo-controlled FREEDOM (Fracture... Lees meer

    Gepost op 10 april 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Abaloparatide in Postmenopausal Women With Osteoporosis and Type 2 Diabetes: A Post Hoc Analysis of the ACTIVE Study.

    JBMR Plus. 2020 Apr;4(4):e10346 Authors: Dhaliwal R, Hans D, Hattersley G, Mitlak B, Fitzpatrick LA, Wang Y, Schwartz AV, Miller PD, Josse RG Type 2 diabetes mellitus (T2DM) increases fracture risk despite normal or... Lees meer

    Gepost op 10 april 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Effects of High Intensity Resistance Training on Osteopenia and Sarcopenia parameters in Older Men with Osteosarcopenia - One-year results of the randomized controlled Franconian Osteopenia and Sarcopenia Trial (FrOST).

    J Bone Miner Res. 2020 Apr 09;: Authors: Kemmler W, Kohl M, Fröhlich M, Jakob F, Engelke K, von Stengel S, Schoene D Dynamic resistance exercise (DRT) might be the most promising agent for fighting sarcopenia in... Lees meer

    Gepost op 10 april 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Treatments of osteoporosis increase bone material strength index in patients with low bone mass.

    Osteoporos Int. 2020 Apr 08;: Authors: Schoeb M, Malgo F, Peeters JJM, Winter EM, Papapoulos SE, Appelman-Dijkstra NM NTRODUCTION: Bone material strength index (BMSi), measured by IMI in vivo, is reduced in patients with... Lees meer

    Gepost op 10 april 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Identification of prevalent vertebral fractures using Vertebral Fracture Assessment (VFA) in asymptomatic postmenopausal women: A systematic review and meta-analysis.

    Bone. 2020 Apr 05;:115358 Authors: Yang J, Mao Y, Nieves JW BACKGROUND: Vertebral fracture (VF) is the most common osteoporotic fracture in postmenopausal women, although most VFs are subclinical. Prevalent VFs are a... Lees meer

    Gepost op 10 april 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • The challenge of long-term adherence: The role of bone turnover markers in monitoring bisphosphonate treatment of osteoporosis.

    Bone. 2020 Mar 28;:115336 Authors: Fontalis A, Eastell R Oral Bisphosphonates (BPs) are the mainstay of osteoporotic treatment, however long-term adherence remains a challenge, primarily owing to the chronic character of... Lees meer

    Gepost op 03 april 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Real-world effectiveness of osteoporosis treatment in the oldest old.

    Osteoporos Int. 2020 Mar 30;: Authors: Ström O, Lauppe R, Ljunggren Ö, Spångéus A, Ortsäter G, O'Kelly J, Åkesson K  INTRODUCTION: To study real-world effectiveness of... Lees meer

    Gepost op 03 april 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Can bone mineral density loss in the non-weight bearing distal forearm predict mortality?

    Bone. 2020 Mar 30;:115347 Authors: Hauger AV, Bergland A, Holvik K, Emaus N, Strand BH PURPOSE: Low bone mineral density (BMD) is associated with increased risk of fractures and mortality. We investigated if rate of BMD... Lees meer

    Gepost op 03 april 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Morphometric vertebral fractures in patients with castration-resistant prostate cancer undergoing treatment with radium-223: a longitudinal study in the real-life clinical practice.

    Endocrine. 2020 Apr 01;: Authors: Mazziotti G, Rodari M, Gelardi F, Tosi G, Zucali PA, Pepe G, Chiti A PURPOSE: Radium-223 was associated with high incidence of non-vertebral fractures in patients with... Lees meer

    Gepost op 03 april 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Risk of falls in postmenopausal women treated with romosozumab: Preliminary indices from a meta-analysis of randomized, controlled trials.

    Osteoporos Sarcopenia. 2020 Mar;6(1):20-26 Authors: Möckel L, Bartneck M, Möckel C Objectives: Falls are the well-known risk factor for osteoporotic fractures and some medications can increase the risk of falls.... Lees meer

    Gepost op 01 april 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Describing the resource utilisation and costs associated withvertebral fractures: the Build Better Bones with Exercise (B3E) Pilot Trial.

    Osteoporos Int. 2020 Mar 26;: Authors: Hassan S, Seung SJ, Clark RE, Gibbs JC, McArthur C, Mittmann N, Thabane L, Kendler D, Papaioannou A, Wark JD, Ashe MC, Adachi JD, Templeton JA, Giangregorio LM INTRODUCTION: This... Lees meer

    Gepost op 29 maart 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Predictors of risk of fracture in inflammatory bowel diseases: a prospective study using FRAX score.

    Minerva Gastroenterol Dietol. 2020 Mar 24;: Authors: Ribaldone DG, Procopio M, Pellicano R, Barale M, Giudici G, Morino M, Saracco GM, Astegiano M BACKGROUND: Despite the well-known risk of osteoporosis and bone fractures... Lees meer

    Gepost op 29 maart 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Effects of denosumab on bone metabolism and bone mineral density in kidney transplant patients: a systematic review and meta-analysis.

    Arch Osteoporos. 2019 03 09;14(1):35 Authors: Thongprayoon C, Acharya P, Aeddula NR, Torres-Ortiz A, Bathini T, Sharma K, Ungprasert P, Watthanasuntorn K, Suarez MLG, Salim SA, Kaewput W, Chenbhanich J, Mao MA, Cheungpasitporn... Lees meer

    Gepost op 24 maart 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Suboptimal medication adherence may favor the progression of vertebral fractures in women with post-menopausal osteoporosis under treatment with denosumab: a real-life observational study.

    Minerva Endocrinol. 2020 Mar 17;: Authors: Betella N, Biamonte E, Matarazzo C, Piccini S, Olivetti R, Cellini M, Lania AG, Mazziotti G BACKGROUND: Medication adherence is a determinant of therapeutic outcomes in patients... Lees meer

    Gepost op 20 maart 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Effects of dairy products on bone mineral density in healthy postmenopausal women: a systematic review and meta-analysis of randomized controlled trials.

    Arch Osteoporos. 2020 Mar 18;15(1):48 Authors: Shi Y, Zhan Y, Chen Y, Jiang Y PURPOSE: To investigate the effects of dairy products on bone mineral density (BMD) in healthy postmenopausal women. METHODS: The EMBASE,... Lees meer

    Gepost op 20 maart 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Secular trends in the initiation of therapy in secondary fracture prevention in Europe: a multi-national cohort study including data from Denmark, Catalonia, and the United Kingdom.

    Osteoporos Int. 2020 Mar 17;: Authors: Skjødt MK, Khalid S, Ernst M, Rubin KH, Martinez-Laguna D, Delmestri A, Javaid MK, Cooper C, Libanati C, Toth E, Abrahamsen B, Prieto-Alhambra D NTRODUCTION: Patients... Lees meer

    Gepost op 20 maart 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Repurposing a fracture risk calculator (FRAX) as a screening tool for women at risk for sarcopenia.

    Osteoporos Int. 2020 Mar 17;: Authors: Pasco JA, Mohebbi M, Tembo MC, Holloway-Kew KL, Hyde NK, Williams LJ, Kotowicz MA   PURPOSE: There is a need for simple screening tools for sarcopenia. As osteoporosis and... Lees meer

    Gepost op 20 maart 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Fragility fractures in France: epidemiology, characteristics and quality of life (the EPIFRACT study).

    Arch Osteoporos. 2020 Mar 13;15(1):46 Authors: Cortet B, Chauvin P, Feron JM, Grange L, Coulomb A, Launois R, Alliot-Launois F, Sellami R, Touboul C, Vincent B, Joubert JM, Briot K PURPOSE: To estimate the incidence of... Lees meer

    Gepost op 18 maart 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Early vertebroplasty within 3 weeks of fracture for acute painful vertebral osteoporotic fractures: subgroup analysis of the VAPOUR trial and review of the literature.

    Eur Spine J. 2020 Mar 13;: Authors: Diamond T, Clark W, Bird P, Gonski P, Barnes E, Gebski V BACKGROUND: VAPOUR found vertebroplasty (V) more effective than placebo (P) in patients with severe pain and fracture duration... Lees meer

    Gepost op 18 maart 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Inflammatory Bowel Disease: A Nationwide Study of Hip Fracture and Mortality Risk after Hip Fracture.

    J Crohns Colitis. 2020 Mar 14;: Authors: Bartko J, Reichardt B, Kocijan R, Klaushofer K, Zwerina J, Behanova M BACKGROUND AND AIMS: With rising rates of inflammatory bowel diseases (IBD) in older adults, management of... Lees meer

    Gepost op 18 maart 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • The role of gut microbiota in bone homeostasis.

    Bone. 2020 Mar 10;:115317 Authors: Behera J, Ison J, Tyagi SC, Tyagi N The gut microbiota (GM) is referred to as the second gene pool of the human body and a commensal, symbiotic, and pathogenic microorganism living in... Lees meer

    Gepost op 18 maart 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Association between oral anticoagulants and osteoporosis: Real-world data mining using a multi-methodological approach.

    Int J Med Sci. 2020;17(4):471-479 Authors: Yokoyama S, Ieda S, Nagano M, Nakagawa C, Iwase M, Hosomi K, Takada M Introduction: Warfarin and direct oral anticoagulants (DOACs) have been widely used in antithrombotic... Lees meer

    Gepost op 18 maart 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Fracture risk following high-trauma versus low-trauma fracture: a registry-based cohort study.

    Osteoporos Int. 2020 Mar 16;: Authors: Leslie WD, Schousboe JT, Morin SN, Martineau P, Lix LM, Johansson H, McCloskey EV, Harvey NC, Kanis JA INTRODUCTION: Some have questioned the usefulness of distinguishing high-trauma... Lees meer

    Gepost op 18 maart 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Association between grip strength and bone mineral density in general US population of NHANES 2013-2014.

    Arch Osteoporos. 2020 Mar 16;15(1):47 Authors: Luo Y, Jiang K, He M  INTRODUCTION: Grip test measures the maximum isotonic strength of hand and forearm and is often used as an indicator of general muscle strength.... Lees meer

    Gepost op 18 maart 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Consensus statement from 2nd International Conference on Controversies in Vitamin D.

    Rev Endocr Metab Disord. 2020 Mar 17;: Authors: Giustina A, Adler RA, Binkley N, Bollerslev J, Bouillon R, Dawson-Hughes B, Ebeling PR, Feldman D, Formenti AM, Lazaretti-Castro M, Marcocci C, Rizzoli R, Sempos CT, Bilezikian... Lees meer

    Gepost op 18 maart 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Distribution of Prevalent and Incident Vertebral Fractures and Their Association with Bone Mineral Density in Postmenopausal Women in the Teriparatide Versus Risedronate VERO Clinical Trial.

    Calcif Tissue Int. 2020 Mar 10;: Authors: Geusens P, Kendler DL, Fahrleitner-Pammer A, López-Romero P, Marin F Vertebral fractures (VFx) occur most frequently in the mid-thoracic and thoraco-lumbar regions, which... Lees meer

    Gepost op 15 maart 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • The Effect of Plasma Lipids and Lipid-Lowering Interventions on Bone Mineral Density: A Mendelian Randomization Study.

    J Bone Miner Res. 2020 Mar 12;: Authors: Zheng J, Brion MJ, Kemp JP, Warrington NM, Borges MC, Hemani G, Richardson TG, Rasheed H, Qiao Z, Haycock P, Ala-Korpela M, Davey Smith G, Tobias JH, Evans DM   Several... Lees meer

    Gepost op 15 maart 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Genetic Burden Contributing to Extremely Low or High Bone Mineral Density in a Senior Male Population From the Osteoporotic Fractures in Men Study (MrOS).

    JBMR Plus. 2020 Mar;4(3):e10335 Authors: Chen S, Jain M, Jhangiani S, Akdemir ZC, Campeau PM, Klein RF, Nielson C, Dai H, Muzny DM, Boerwinkle E, Gibbs RA, Orwoll ES, Lupski JR, Posey JE, Lee B Worldwide, one in five men... Lees meer

    Gepost op 15 maart 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • RANKL/RANK/OPG Pathway: A Mechanism Involved in Exercise-Induced Bone Remodeling.

    Biomed Res Int. 2020;2020:6910312 Authors: Tobeiha M, Moghadasian MH, Amin N, Jafarnejad S Bones as an alive organ consist of about 70% mineral and 30% organic component. About 200 million people are suffering from... Lees meer

    Gepost op 11 maart 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Recognizing osteoporotic vertebral deformity on frontal view radiograph: a cohort analysis and a pictorial review.

    Arch Osteoporos. 2020 Mar 06;15(1):41 Authors: Wáng YXJ, Du MM, Che-Nordin N, Ye PP, Qiu SW, Griffith JF, Yan ZH PURPOSE: Opportunities exist to detect osteoporotic vertebral deformities (VDs) on frontal radiograph... Lees meer

    Gepost op 08 maart 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Trends in Bone Mineral Density, Osteoporosis, and Osteopenia Among U.S. Adults With Prediabetes, 2005-2014.

    Diabetes Care. 2020 Mar 06;: Authors: Chen C, Chen Q, Nie B, Zhang H, Zhai H, Zhao L, Xia P, Lu Y, Wang N OBJECTIVE: We aimed to evaluate trends in bone mineral density (BMD) and the prevalence of osteoporosis/osteopenia... Lees meer

    Gepost op 08 maart 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Prevention and management of osteoporotic fractures by non-physician health professionals: a systematic literature review to inform EULAR points to consider.

    RMD Open. 2020 Jan;6(1): Authors: Wilson N, Hurkmans E, Adams J, Bakkers M, Balážová P, Baxter M, Blavnsfeldt AB, Briot K, Chiari C, Cooper C, Dragoi R, Gäbler G, Lems W, Mosor E, Pais S, Simon C, Studenic... Lees meer

    Gepost op 08 maart 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Effect of eldecalcitol on muscle function and fall prevention in Japanese postmenopausal women: A randomized controlled trial.

    J Orthop Sci. 2020 Mar 02;: Authors: Saito T, Mori Y, Irei O, Baba K, Nakajo S, Itoi E BACKGROUD: Exercises and vitamin D interventions have shown to improve muscle function and balance, and prevent falls in... Lees meer

    Gepost op 07 maart 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • The Role of Mast Cells in Bone Metabolism and Bone Disorders.

    Front Immunol. 2020;11:163 Authors: Ragipoglu D, Dudeck A, Haffner-Luntzer M, Voss M, Kroner J, Ignatius A, Fischer V Mast cells (MCs) are important sensor and effector cells of the immune system that are involved in many... Lees meer

    Gepost op 05 maart 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Added Value of Impact Microindentation in the Evaluation of Bone Fragility: A Systematic Review of the Literature.

    Front Endocrinol (Lausanne). 2020;11:15 Authors: Schoeb M, Hamdy NAT, Malgo F, Winter EM, Appelman-Dijkstra NM The current gold standard for the diagnosis of osteoporosis and the prediction of fracture risk is the... Lees meer

    Gepost op 05 maart 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Can Dietary Intake of Vitamin C-Oriented Foods Reduce the Risk of Osteoporosis, Fracture, and BMD Loss? Systematic Review With Meta-Analyses of Recent Studies.

    Front Endocrinol (Lausanne). 2019;10:844 Authors: Zeng LF, Luo MH, Liang GH, Yang WY, Xiao X, Wei X, Yu J, Guo D, Chen HY, Pan JK, Huang HT, Liu Q, Guan ZT, Han YH, Zhao D, Zhao JL, Hou SR, Wu M, Lin JT, Li JH, Liang WX, Ou... Lees meer

    Gepost op 05 maart 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • The U-shaped relationship between levels of bouted activity and fall incidence in community-dwelling older adults: a prospective cohort study.

    J Gerontol A Biol Sci Med Sci. 2020 Mar 02;: Authors: Lu Z, Lam FMH, Leung JCS, Kwok TCY BACKGROUND: It remains uncertain whether the association between physical activity (PA) and falls is U-shaped, and few studies have... Lees meer

    Gepost op 05 maart 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • The microbiome adds to the complexity of parathyroid hormone action on bone.

    J Clin Invest. 2020 Mar 03;: Authors: Khosla S Parathyroid hormone (PTH) has complex effects on bone, including stimulating bone formation and regulating the hematopoietic stem cell (HSC) niche. In the current issue of... Lees meer

    Gepost op 05 maart 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Breast cancer outcome in relation to bone mineral density and bisphosphonate use: a sub-study of the DATA trial.

    Breast Cancer Res Treat. 2020 Mar 02;: Authors: van Hellemond IEG, Smorenburg CH, Peer PGM, Swinkels ACP, Seynaeve CM, van der Sangen MJC, Kroep JR, de Graaf H, Honkoop AH, Erdkamp FLG, van den Berkmortel FWPJ, de Roos WK,... Lees meer

    Gepost op 05 maart 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Effects of long-term inhaled corticosteroid treatment on fragility fractures in older women: the Manitoba BMD registry study.

    Osteoporos Int. 2020 Mar 02;: Authors: Ng BC, Leslie WD, Johnson KM, FitzGerald JM, Sadatsafavi M, Chen W  INTRODUCTION: Inhaled corticosteroids (ICS) are frequently used in older women with chronic respiratory... Lees meer

    Gepost op 05 maart 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Osteoporosis and the Potential of Cell-Based Therapeutic Strategies.

    Int J Mol Sci. 2020 Feb 28;21(5): Authors: Macías I, Alcorta-Sevillano N, Rodríguez CI, Infante A Osteoporosis, the most common chronic metabolic bone disease, is characterized by low bone mass and increased... Lees meer

    Gepost op 05 maart 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Effects of Odanacatib on Bone Structure and Quality in Postmenopausal Women with Osteoporosis: 5-year Data from the Phase 3 Long-Term Odanacatib Fracture Trial (LOFT) and its Extension.

    J Bone Miner Res. 2020 Mar 02;: Authors: Recker R, Dempster D, Langdahl B, Giezek H, Clark S, Ellis G, de Villiers T, Valter I, Zerbini CAF, Cohn D, Santora A, Duong LT Odanacatib (ODN), a selective oral inhibitor of... Lees meer

    Gepost op 05 maart 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Proteomic and Transcriptomic Approaches for Studying Bone Regeneration in Health and Systemically Compromised Conditions.

    Proteomics Clin Appl. 2020 Mar 04;:e1900084 Authors: Elena C, Nikolaos D Bone regeneration is a complex biological process, where the molecular mechanisms are only partially understood. In an ageing population, where the... Lees meer

    Gepost op 05 maart 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Pelvic fractures and changes in bone mineral density after radiotherapy for cervical, endometrial, and vaginal cancer: A prospective study of 239 women.

    Cancer. 2020 Mar 03;: Authors: Salcedo MP, Sood AK, Jhingran A, Eifel PJ, Klopp AH, Iyer RB, Felllman BM, Jimenez C, Schmeler KM BACKGROUND: Advances in radiotherapy (RT) have led to improved oncologic outcomes for women... Lees meer

    Gepost op 05 maart 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • In vitro and in vivo studies using non-traditional bisphosphonates.

    Bone. 2020 Feb 26;:115301 Authors: Plotkin LI, Buvinic S, Balanta-Melo J Non-traditional bisphosphonates, that is, bisphosphonates that do not inhibit osteoclast viability or function, were initially reported in the 1990s... Lees meer

    Gepost op 01 maart 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Telomere length and telomerase activity in osteoporosis and osteoarthritis.

    Exp Ther Med. 2020 Mar;19(3):1626-1632 Authors: Fragkiadaki P, Nikitovic D, Kalliantasi K, Sarandi E, Thanasoula M, Stivaktakis PD, Nepka C, Spandidos DA, Tosounidis T, Tsatsakis A Osteoarthritis (OA) and osteoporosis... Lees meer

    Gepost op 29 februari 2020

    Bron: https://www.ncbi.nlm.nih.go....

  • Favorable skeletal benefit/risk of long-term denosumab therapy: A virtual-twin analysis of fractures prevented relative to skeletal safety events observed.

    Ferrari S, Lewiecki Em, Butter PW, Kender DL, Napoli N, Huang S, Crittenden DB, Pannaculli N, Siris E, Berkley N. Bone. 2020 Feb 21:115287.    Antiresorptive therapies reduce fracture risk; however, long-term... Lees meer

    Gepost op 28 februari 2020

    Bron: https://radar.avrotros.nl/h....

  • Aspirin and fracture risk: a systematic review and exploratory meta-analysis of observational studies.

    Barker AL, Soh SE, Sanders KM, Pasco J, Khosla S, Ebeling PR, Ward SA, Peeters G, Talevski J, Cumming RG, SeemanE, McNell JJ. BMJ Open. 2020 Feb 20;10(2):e026876. OBJECTIVES: This review provides insights into the... Lees meer

    Gepost op 28 februari 2020

    Bron: https://plusmagazine.knack.....

  • Cardiovascular and skeletal safety of zoledronic acid in osteoporosis observational, matched cohort study using Danish and Swedish health registries.

    Rubin KH, Moller S, Choudhury A, Zorina O, Kalsekar S, Eriksen EF, Andersen M, Abrahamsen B. Bone  2020 Feb 22:115296. Background: This observational safety study used national registers to compare the real world... Lees meer

    Gepost op 28 februari 2020

    Bron: https://plusmagazine.knack.....

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