Osteoporose Nieuws
Wekelijks verschijnen er nieuwe onderzoek, publicaties en artikelen over osteoporose. Een selectie uit dit aanbod wordt doorgeplaatst op deze website. Klik hier voor de rss-nieuwsfeeds.
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Assessment of the genetic and clinical determinants of fracture risk: genome wide association and mendelian randomisation study.
BMJ. 2018 08 29;362:k3225 Authors: Trajanoska K, Morris JA, Oei L, Zheng HF, Evans DM, Kiel DP, Ohlsson C, Richards JB, Rivadeneira F, GEFOS/GENOMOS consortium and the 23andMe research team OBJECTIVES: To identify the... Lees meer
Gepost op 15 maart 2019
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Evidence of patient beliefs, values, and preferences is not provided in osteoporosis clinical practice guidelines.
Osteoporos Int. 2019 Mar 11;: Authors: Sale JEM, Marwah A, Naeem F, Yu W, Meadows L INTRODUCTION: Our objectives were to determine (1) the extent to which osteoporosis guidelines reflected patients' beliefs, values,... Lees meer
Gepost op 14 maart 2019
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Association of Bone Metastasis With Early-Stage Breast Cancer in Women With and Without Precancer Osteoporosis According to Osteoporosis Therapy Status.
JAMA Netw Open. 2019 Mar 01;2(3):e190429 Authors: Chen HM, Chen FP, Yang KC, Yuan SS Importance: Deaths from cancer are attributed more to secondary than primary tumors, but the pathogenesis of organ-specific cancer... Lees meer
Gepost op 11 maart 2019
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Fracture Risk Indices From DXA-Based Finite Element Analysis Predict Incident Fractures Independently From FRAX: The Manitoba BMD Registry.
J Clin Densitom. 2019 Feb 08;: Authors: Leslie WD, Luo Y, Yang S, Goertzen AL, Ahmed S, Delubac I, Lix LM OBJECTIVE: Finite element analysis (FEA) is a computational method to predict the behavior of materials under... Lees meer
Gepost op 11 maart 2019
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Higher rates of osteoporosis treatment initiation and persistence in patients with newly diagnosed vertebral fracture when introduced in inpatients than later in outpatients.
Osteoporos Int. 2019 Feb 28;: Authors: Spechbach H, Fabreguet I, Saule E, Hars M, Stirnemann J, Ferrari S, Rizzoli R, Chevalley T INTRODUCTION: Fracture liaison services are standard care for secondary fracture... Lees meer
Gepost op 03 maart 2019
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Denosumab vs risedronate in glucocorticoid-induced osteoporosis: final results of a 24-month randomized, double-blind, double-dummy trial.
Arthritis Rheumatol. 2019 Feb 28;: Authors: Saag KG, Pannacciulli N, Geusens P, Adachi JD, Messina OD, Morales-Torres J, Emkey R, Butler PW, Yin X, Lems WF OBJECTIVE: In glucocorticoid-treated subjects, denosumab 60 mg... Lees meer
Gepost op 03 maart 2019
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Effects of a 3-month weight-bearing and resistance exercise training on circulating osteogenic cells and bone formation markers in postmenopausal women with low bone mass.
Osteoporos Int. 2019 Feb 26;: Authors: Pasqualini L, Ministrini S, Lombardini R, Bagaglia F, Paltriccia R, Pippi R, Collebrusco L, Reginato E, Sbroma Tomaro E, Marini E, D'Abbondanza M, Scarponi AM, De Feo P, Pirro M... Lees meer
Gepost op 01 maart 2019
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Radiological criteria for atypical features of femur fractures: what we can learn when applied in a clinical study setting.
Osteoporos Int. 2019 Feb 26;: Authors: LeBlanc ES, Rosales AG, Genant HK, Dell RM, Friess DM, Boardman DL, Santora AC, Bauer DC, de Papp AE, Black DM, Orwoll ES A INTRODUCTION: Assess American Society of Bone and Mineral... Lees meer
Gepost op 01 maart 2019
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Insights into the bisphosphonate holiday: a preliminary FTIRI study.
Osteoporos Int. 2018 03;29(3):699-705 Authors: Boskey AL, Spevak L, Ma Y, Wang H, Bauer DC, Black DM, Schwartz AV INTRODUCTION: Bisphosphonates (BP) are the most commonly used and effective drugs to prevent fragility... Lees meer
Gepost op 27 februari 2019
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Diagnosis and Management of Paget's Disease of Bone in Adults: A Clinical Guideline.
J Bone Miner Res. 2019 Feb 25;:e3657 Authors: Ralston SH, Corral-Gudino L, Cooper C, Francis RM, Fraser WD, Gennari L, Guañabens N, Javaid MK, Layfield R, O'Neill TW, Russell RGG, Stone MD, Simpson K, Wilkinson D,... Lees meer
Gepost op 27 februari 2019
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Adherence to the recommended prevention strategies before and after a hip fragility fracture: what makes us go blind?
Acta Reumatol Port. 2018 Apr-Jun;43(2):93-101 Authors: Daniel A, Marques ML, Brites L, Torres C, Marques A, Pereira da Silva JA OBJECTIVES: Our main objective was to evaluate the percentage of patients under... Lees meer
Gepost op 24 februari 2019
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Executive summary of the European guidance for the diagnosis and management of osteoporosis in postmenopausal women.
Calcif Tissue Int. 2019 Feb 22;: Authors: Kanis JA, Cooper C, Rizzoli R, Reginster JY, Scientific Advisory Board of the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) and the... Lees meer
Gepost op 24 februari 2019
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Adjuvant denosumab in postmenopausal patients with hormone receptor-positive breast cancer (ABCSG-18): disease-free survival results from a randomised, double-blind, placebo-controlled, phase 3 trial.
Lancet Oncol. 2019 Feb 19;: Authors: Gnant M, Pfeiler G, Steger GG, Egle D, Greil R, Fitzal F, Wette V, Balic M, Haslbauer F, Melbinger-Zeinitzer E, Bjelic-Radisic V, Jakesz R, Marth C, Sevelda P, Mlineritsch B, Exner R, Fesl... Lees meer
Gepost op 24 februari 2019
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An Optimised Fracture Liaison Service Model: Maintained Diagnostic Sensitivity Despite Reduced Number of Diagnostic Tests Performed.
Calcif Tissue Int. 2019 Feb 19;: Authors: Tei RMH, Plana-Ripoll O, Brink O, Langdahl BL Patients suffering a low-energy fracture are at high risk of subsequent fractures. Investigation of all fragility fracture patients... Lees meer
Gepost op 21 februari 2019
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Elimination of senescent osteoclast progenitors has no effect on the age-associated loss of bone mass in mice.
Aging Cell. 2019 Feb 17;:e12923 Authors: Kim HN, Chang J, Iyer S, Han L, Campisi J, Manolagas SC, Zhou D, Almeida M Both an increase in osteoclast and a decrease in osteoblast numbers contribute to skeletal aging. Markers... Lees meer
Gepost op 20 februari 2019
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Increased the risk of osteoporosis with hysterectomy: A longitudinal follow-up study using a national sample cohort.
Am J Obstet Gynecol. 2019 Feb 12;: Authors: Choi HG, Jung YJ, Lee SW BACKGROUND: Premenopausal hysterectomy is associated with a decreased ovarian reserve, follicular atresia, and subsequently reduced long-term estrogen... Lees meer
Gepost op 16 februari 2019
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Assessment and Management of Bone Health in Women with Early Breast Cancer Receiving Endocrine Treatment in the DATA Study.
Int J Cancer. 2019 Feb 12;: Authors: van Hellemond IEG, Smorenburg CH, Peer PGM, Swinkels ACP, Seynaeve CM, van der Sangen MJC, Kroep JR, De Graaf H, Honkoop AH, Erdkamp FLG, van den Berkmortel FWPJ, de Boer M, de Roos WK,... Lees meer
Gepost op 15 februari 2019
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High prevalence of vertebral fractures and low trabecular bone score in patients with fragility fractures: A cross-sectional sub-study of NoFRACT.
Bone. 2019 Feb 08;: Authors: Borgen TT, Bjørnerem Å, Solberg LB, Andreasen C, Brunborg C, Stenbro MB, Hübschle LM, Froholdt A, Figved W, Apalset EM, Gjertsen JE, Basso T, Lund I, Hansen AK, Stutzer JM, Dahl... Lees meer
Gepost op 15 februari 2019
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Invasive Oral Procedures and Events in Women With Postmenopausal Osteoporosis Treated With Denosumab for up to 10 Years.
J Clin Endocrinol Metab. 2019 Feb 13;: Authors: Watts NB, Grbic JT, Binkley N, Papapoulos S, Butler PW, Yin X, Tierney A, Wagman RB, McClung M Context: Antiresorptive therapy has been associated with osteonecrosis of the... Lees meer
Gepost op 15 februari 2019
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The efficacy and safety of menatetrenone in the management of osteoporosis: a systematic review and meta-analysis of randomized controlled trials.
Osteoporos Int. 2019 Feb 07;: Authors: Su S, He N, Men P, Song C, Zhai S INTRODUCTION: We performed a systematic review and meta-analysis of the efficacy and safety of menatetrenone in managing osteoporosis. METHODS:... Lees meer
Gepost op 10 februari 2019
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All-cause mortality with current and past use of antidepressants or benzodiazepines after major osteoporotic and hip fracture.
Osteoporos Int. 2019 Feb 08;: Authors: de Bruin IJA, Klop C, Wyers CE, Overbeek JA, Geusens PPMM, van den Bergh JPW, Driessen JHM, de Vries F INTRODUCTION: It remains unclear to what extent use of antidepressants... Lees meer
Gepost op 10 februari 2019
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The effect of insulin on bone mineral density among women with type 2 diabetes: a SWAN Pharmacoepidemiology study.
Osteoporos Int. 2018 02;29(2):347-354 Authors: Ruppert K, Cauley J, Lian Y, Zgibor JC, Derby C, Solomon DH INTRODUCTION: Women with diabetes mellitus (DM) have higher bone mineral density (BMD) and experience slower BMD... Lees meer
Gepost op 07 februari 2019
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Effect of abaloparatide on vertebral, nonvertebral, major osteoporotic, and clinical fractures in a subset of postmenopausal women at increased risk of fracture by FRAX probability.
Arch Osteoporos. 2019 Feb 05;14(1):15 Authors: McCloskey EV, Fitzpatrick LA, Hu MY, Williams G, Kanis JA We evaluated the efficacy of abaloparatide in women who were at increased risk for fracture, based on CHMP... Lees meer
Gepost op 07 februari 2019
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Risk Factors for Poor Functional Recovery, Mortality, Recurrent Fractures, and Falls Among Patients Participating in a Fracture Liaison Service Program.
J Am Med Dir Assoc. 2019 Feb 02;: Authors: Chao CT, Yang RS, Huang WJ, Tsai KS, Chan DD OBJECTIVE: A fracture liaison service (FLS) for patients with fractures is a promising approach for improving outcomes, but barriers... Lees meer
Gepost op 07 februari 2019
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Osteoporosis.
Lancet. 2019 Jan 26;393(10169):364-376 Authors: Compston JE, McClung MR, Leslie WD Fractures resulting from osteoporosis become increasingly common in women after age 55 years and men after age 65 years, resulting in... Lees meer
Gepost op 02 februari 2019
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Risk of imminent fracture following a previous fracture in a Swedish database study.
Osteoporos Int. 2019 Jan 24;: Authors: Banefelt J, Åkesson KE, Spångéus A, Ljunggren O, Karlsson L, Ström O, Ortsäter G, Libanati C, Toth E INTRODUCTION: This study aims to determine the... Lees meer
Gepost op 31 januari 2019
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Bone turnover markers are differentially affected by pre-analytical handling.
Osteoporos Int. 2019 Jan 24;: Authors: Christensen GL, Halgreen JR, Milenkovski M, Köse A, Quardon N, Jørgensen NR INTRODUCTION: Bone turnover markers are often shipped to central laboratories for analysis,... Lees meer
Gepost op 31 januari 2019
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Intervals between bone mineral density testing with dual-energy X-ray absorptiometry scans in clinical practice.
Osteoporos Int. 2019 Jan 24;: Authors: Lyu H, Yoshida K, Tedeschi SK, Zhao S, Xu C, Nigwekar SU, Leder BZ, Solomon DH INTRODUCTION: Serial dual-energy X-ray absorptiometry (DXA) measurements are suggested for patients at... Lees meer
Gepost op 31 januari 2019
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Effects of denosumab and alendronate on bone health and vascular function in hemodialysis patients: A randomized, controlled trial.
J Bone Miner Res. 2019 Jan 28;: Authors: Iseri K, Watanabe M, Yoshikawa H, Mitsui H, Endo T, Yamamoto Y, Iyoda M, Ryu K, Inaba T, Shibata T Mineral and bone disorders including osteoporosis are common in dialysis patients... Lees meer
Gepost op 31 januari 2019
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Chronic kidney disease is associated with low BMD at the hip but not at the spine.
Osteoporos Int. 2019 Jan 28;: Authors: Bezerra de Carvalho KS, Vasco RFV, Custodio MR, Jorgetti V, Moysés RMA, Elias RM INTRODUCTION: Osteoporosis is a highly prevalent disease in patients with chronic kidney... Lees meer
Gepost op 31 januari 2019
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Osteoporotic vertebral deformity with endplate/cortex fracture is associated with higher further vertebral fracture risk: the Ms. OS (Hong Kong) study results.
Osteoporos Int. 2019 Jan 22;: Authors: Wáng YXJ, Che-Nordin N, Deng M, Leung JCS, Kwok AWL, He LC, Griffith JF, Kwok TCY, Leung PC A INTRODUCTION: The progression and incidence of osteoporotic vertebral... Lees meer
Gepost op 25 januari 2019
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Mechanisms Underlying Normal Fracture Healing and Risk Factors for Delayed Healing.
Curr Osteoporos Rep. 2019 Jan 22;: Authors: Cheng C, Shoback D PURPOSE OF REVIEW: Substantial advances have been made in understanding the biological basis of fracture healing. Yet, it is unclear whether the presence of... Lees meer
Gepost op 25 januari 2019
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Change in Bone Density and Reduction in Fracture Risk: A Meta-Regression of Published Trials.
J Bone Miner Res. 2019 Jan 23;: Authors: Bouxsein ML, Eastell R, Lui LY, Wu LA, de Papp AE, Grauer A, Marin F, Cauley JA, Bauer DC, Black DM, FNIH Bone Quality Project Meta-analyses conducted >15 years ago... Lees meer
Gepost op 25 januari 2019
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Systemic comorbidities are associated with medication-related osteonecrosis of the jaws: case-control study.
Oral Dis. 2019 Jan 23;: Authors: McGowan K, Acton C, Ivanovski S, Johnson NW, Ware RS OBJECTIVES: Medication-related osteonecrosis of the jaws (MRONJ) is a serious condition developed in up to 15% of patients who take... Lees meer
Gepost op 25 januari 2019
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Treatment with zoledronic acid subsequent to odanacatib prevents bone loss in postmenopausal women with osteoporosis.
Osteoporos Int. 2019 Jan 17;: Authors: Koldkjær Sølling AS, Harsløf T, Langdahl B INTRODUCTION: The development of odanacatib (ODN), a cathepsin K inhibitor, for treatment of osteoporosis was... Lees meer
Gepost op 22 januari 2019
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Lower baseline value and greater decline in BMD as independent risk factors for mortality in community dwelling elderly.
Bone. 2019 Jan 17;: Authors: Kim KM, Moon JH, Choi SH, Lim S, Lim JY, Kim KW, Jang HC Skeleton plays diverse roles via crosstalk between others, thus it is conceivable that lower BMD per se may reflect negative influences... Lees meer
Gepost op 22 januari 2019
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Cellular senescence in bone.
Bone. 2019 Jan 16;: Authors: Farr JN, Khosla S Cellular senescence refers to a process induced by various types of stress that causes irreversible cell cycle arrest and distinct cellular alterations, including profound... Lees meer
Gepost op 22 januari 2019
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Serum 25-hydroxy-vitamin D and the risk of fractures in the teriparatide versus risedronate VERO clinical trial.
Arch Osteoporos. 2019 Jan 18;14(1):10 Authors: Minisola S, Marin F, Kendler DL, Geusens P, Zerbini CAF, Russo LA, Casado E, Fahrleitner-Pammer A, Stepan JJ, Lespessailles E, Moericke R, Bagur A, Lakatos P, López-Romero... Lees meer
Gepost op 22 januari 2019
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Dietary Patterns in Relation to Low Bone Mineral Density and Fracture Risk: A Systematic Review and Meta-Analysis.
Adv Nutr. 2019 Jan 17;: Authors: Fabiani R, Naldini G, Chiavarini M Low bone mineral density (BMD) and osteoporosis-related fractures constitute a considerable public health burden. Several studies have demonstrated the... Lees meer
Gepost op 22 januari 2019
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Predictors of change of trabecular bone score (TBS) in older men: results from the Osteoporotic Fractures in Men (MrOS) Study.
Osteoporos Int. 2018 01;29(1):49-59 Authors: Schousboe JT, Vo TN, Langsetmo L, Taylor BC, Kats AM, Schwartz AV, Bauer DC, Cauley JA, Ensrud KE, Osteoporotic Fractures in Men (MrOS) Study Research Group INTRODUCTION: Our... Lees meer
Gepost op 16 januari 2019
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Circulating serum vitamin D levels and total body bone mineral density: A Mendelian randomization study.
J Cell Mol Med. 2019 Jan 13;: Authors: Sun JY, Zhao M, Hou Y, Zhang C, Oh J, Sun Z, Sun BL Until recently, randomized controlled trials have not demonstrated convincing evidence that vitamin D, or vitamin D in combination... Lees meer
Gepost op 16 januari 2019
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Outcomes for Elderly Patients With Atypical Femoral Fractures Compared to Typical Femoral Fractures for Length of Stay, Discharge Destination, and 30-Day Mortality Rate.
Geriatr Orthop Surg Rehabil. 2018;9:2151459318820222 Authors: Davenport D, Duncan J, Duncan R, Dick A, Bansal M, Edwards MR Introduction: Despite increasing recognition of atypical femoral fractures (AFFs), there's... Lees meer
Gepost op 13 januari 2019
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Symptoms and Upper Gastrointestinal Mucosal Injury Associated with Bisphosphonate Therapy.
Intern Med. 2019 Jan 10;: Authors: Yamamoto K, Kishino M, Nakamura S, Tokushige K Objective The incidence of osteoporosis is increasing with the rapid aging of the Japanese population. Bisphosphonates are first-line... Lees meer
Gepost op 13 januari 2019
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Clinical utility of bone turnover markers in monitoring the withdrawal of treatment with oral bisphosphonates in postmenopausal osteoporosis.
Osteoporos Int. 2019 Jan 06;: Authors: Naylor KE, McCloskey EV, Jacques RM, Peel NFA, Paggiosi MA, Gossiel F, Walsh JS, Eastell R INTRODUCTION: Measurement of bone turnover markers (BTMs) may be useful to monitor offset... Lees meer
Gepost op 11 januari 2019
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Executive summary of European guidance for the diagnosis and management of osteoporosis in postmenopausal women.
Aging Clin Exp Res. 2019 Jan 05;: Authors: Kanis JA, Cooper C, Rizzoli R, Reginster JY, Scientific Advisory Board of the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) and the... Lees meer
Gepost op 11 januari 2019
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A systematic review and meta-analysis of the effect of bisphosphonate drug holidays on bone mineral density and osteoporotic fracture risk.
Osteoporos Int. 2019 Jan 08;: Authors: Nayak S, Greenspan SL INTRODUCTION: We performed a systematic review and meta-analysis on the effect of drug holidays (discontinuation) on BMD and fracture risk. METHODS: We searched... Lees meer
Gepost op 11 januari 2019
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Differences in prevalence and associated factors between mild and severe vertebral fractures in Japanese men and women: the third survey of the ROAD study.
J Bone Miner Metab. 2019 Jan 03;: Authors: Horii C, Asai Y, Iidaka T, Muraki S, Oka H, Tsutsui S, Hashizume H, Yamada H, Yoshida M, Kawaguchi H, Nakamura K, Akune T, Tanaka S, Yoshimura N Vertebral fracture (VF) is... Lees meer
Gepost op 05 januari 2019
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Metabolic characteristics of subjects with spine-femur bone mineral density discordances: the Korean National Health and Nutrition Examination Survey (KNHANES 2008-2011).
J Bone Miner Metab. 2019 Jan 03;: Authors: Hong AR, Kim JH, Lee JH, Kim SW, Shin CS The diagnosis of osteoporosis is determined based on the lowest bone mineral density (BMD) T-score at the lumbar spine (LS) and hip.... Lees meer
Gepost op 05 januari 2019
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Mortality risk reduction differs according to bisphosphonate class: a 15-year observational study.
Osteoporos Int. 2019 Jan 03;: Authors: Bliuc D, Tran T, van Geel T, Adachi JD, Berger C, van den Bergh J, Eisman JA, Geusens P, Goltzman D, Hanley DA, Josse RG, Kaiser S, Kovacs CS, Langsetmo L, Prior JC, Nguyen TV, Center JR,... Lees meer
Gepost op 05 januari 2019
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Does a dedicated hip fracture unit improve clinical outcomes? A five-year case series.
Ann R Coll Surg Engl. 2019 Jan 03;:1-5 Authors: Walton TJ, Bellringer SF, Edmondson M, Stott P, Rogers BA INTRODUCTION: The aim of the study was to establish whether a dedicated hip fracture unit, geographically separate... Lees meer
Gepost op 04 januari 2019
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Reduction of Cortical Bone Turnover and Erosion Depth After 2 and 3 Years of Denosumab: Iliac Bone Histomorphometry in the FREEDOM Trial.
J Bone Miner Res. 2019 Jan 02;: Authors: Chavassieux P, Portero-Muzy N, Roux JP, Horlait S, Dempster DW, Wang A, Wagman RB, Chapurlat R Denosumab, a RANKL inhibitor, reduced the risk of vertebral, hip, and nonvertebral... Lees meer
Gepost op 04 januari 2019
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Pulsed electromagnetic fields: promising treatment for osteoporosis.
Osteoporos Int. 2019 Jan 02;: Authors: Wang T, Yang L, Jiang J, Liu Y, Fan Z, Zhong C, He C Osteoporosis (OP) is considered to be a well-defined disease which results in high morbidity and mortality. In patients diagnosed... Lees meer
Gepost op 04 januari 2019
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Effect of Bisphosphonates on Fracture Outcomes Among Frail Older Adults.
J Am Geriatr Soc. 2018 Dec 21;: Authors: Zullo AR, Zhang T, Lee Y, McConeghy KW, Daiello LA, Kiel DP, Mor V, Berry SD BACKGROUND: Bisphosphonates are seldom used in frail, older adults, in part due to lack of direct... Lees meer
Gepost op 30 december 2018
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Fracture Prevention with Zoledronate in Older Women with Osteopenia.
N Engl J Med. 2018 Dec 20;379(25):2407-2416 Authors: Reid IR, Horne AM, Mihov B, Stewart A, Garratt E, Wong S, Wiessing KR, Bolland MJ, Bastin S, Gamble GD BACKGROUND: Bisphosphonates prevent fractures in patients with... Lees meer
Gepost op 30 december 2018
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Glucocorticoid-Induced Osteoporosis.
N Engl J Med. 2018 Dec 27;379(26):2547-2556 Authors: Buckley L, Humphrey MB PMID: 30586507 [PubMed - in process] - review Lees meer
Gepost op 30 december 2018
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Hip fracture rates and time trends in use of anti-osteoporosis medications in Denmark for the period 2005 to 2015: Missed opportunities in fracture prevention.
Bone. 2018 Dec 21;120:476-481 Authors: Abrahamsen B, Skjødt MK, Vestergaard P BACKGROUND: Declining use of bisphosphonates (BP) in the United States and Europe may lead to a widening of the treatment gap for... Lees meer
Gepost op 30 december 2018
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Oral bisphosphonates and incidence of cancers in patients with osteoporosis: a systematic review and meta-analysis.
Arch Osteoporos. 2018 Dec 17;14(1):1 Authors: Deng Y, Zhang Z, Jia X, Cheng W, Zhou X, Liu Y, Wang M PURPOSE: Several previous studies have shown that oral bisphosphonates (BPs) are associated with the incidence of 13... Lees meer
Gepost op 21 december 2018