Osteoporose Nieuws
Wekelijks verschijnen er nieuwe onderzoek, publicaties en artikelen over osteoporose. Een selectie uit dit aanbod wordt doorgeplaatst op deze website. Klik hier voor de rss-nieuwsfeeds.
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Switching to denosumab or bisphosphonates after completion of teriparatide treatment in women with severe postmenopausal osteoporosis
Endocr. Pract. 2021 Jun 7;S1530-891X(21)01077-6. Objective: We compared bone mineral density (BMD) changes after 12 months' treatment with denosumab or bisphosphonates in postmenopausal women with severe... Lees meer
Gepost op 12 juni 2021
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Analysis of the subsequent treatment of osteoporosis by transitioning from bisphosphonates to denosumab, using quantitative computed tomography: A prospective cohort study
Bone Rep. 2021 May 7;14:101090. Purpose: Denosumab reduces bone resorption and improves bone mineral density (BMD). Studies have analyzed subsequent treatment transitioning from bisphosphonates to denosumab... Lees meer
Gepost op 12 juni 2021
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Risk of Subsequent Fractures in Postmenopausal Women After Nontraumatic vs Traumatic Fractures
JAMA Intern Med. 2021 jun 7;e212617 Objective: To determine how future fracture risk varies according to whether an initial fracture is traumatic or nontraumatic. Design, setting, and participants: We... Lees meer
Gepost op 10 juni 2021
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Dual-energy X-ray Absorptiometry Does Not Represent Bone Structure in Patients with Osteoporosis: A Comparison of Lumbar Dual-Energy X-Ray Absorptiometry with Vertebral Biopsies
Spine. 2021 Jul 1;46(13):861-866. Study design: Prospective cross-sectional exploratory study. Objective: To evaluate the correlation between in vivo lumbar dual-energy x-ray absorptiometry (DXA)... Lees meer
Gepost op 10 juni 2021
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SCOPE 2021: a new scorecard for osteoporosis in Europe
Arch Osteoporos 2021;june 2;(16)1:82 Introduction: The scorecard for osteoporosis in Europe (SCOPE) is a project of the International Osteoporosis Foundation (IOF) that seeks to raise awareness of osteoporosis care... Lees meer
Gepost op 06 juni 2021
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Fracture Incidence and the Relevance of Dietary and Lifestyle Factors Differ in the United Kingdom and Hong Kong: An International Comparison of Longitudinal Cohort Study Data
Calcif Tissue Int. 2021 Jun 3. doi: 10.1007/s00223-021-00870-z. Online ahead of print. Geographic variation in fracture risk may be due to divergent profiles of dietary, lifestyle, and other risk factors... Lees meer
Gepost op 06 juni 2021
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Patient Outcomes in the Years After a DXA-BMD Treatment Monitoring Test: Improved Medication Adherence in Some, But Too Little Too Late
J Bone Miner Res. 2021 May 24.doi: 10.1002/jbmr.4333. The role of mid-treatment monitoring dual-energy X-ray absorptiometry-bone mineral density (DXA-BMD) for bisphosphonate-treated patients with osteoporosis remains... Lees meer
Gepost op 25 mei 2021
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Effects of prior osteoporosis treatment on 12-month treatment response of romosozumab in patients with postmenopausal osteoporosis
Joint Bone Spine. 2021 May 18;105219. Objectives: To investigate the effects of prior treatment and determine the predictors of a 12-month treatment response of romosozumab (ROMO) in 148 patients... Lees meer
Gepost op 24 mei 2021
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Is there a potential dual effect of denosumab for treatment of osteoporosis and sarcopenia?
Clin Rheumatol. 2021 May 19.doi: 10.1007/s10067-021-05757-w. Background: The prevalence of sarcopenia with osteoporosis results in a higher risk of falling and fractures. It was noted that patients who had... Lees meer
Gepost op 21 mei 2021
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Alterations of bone markers in obese patients with type 2 diabetes after bariatric surgery: A meta-analysis and systemic review of randomized controlled trials and cohorts
Medicine (Baltimore). 2021 May 21;100(20):e26061. Background: The aim of this study is to evaluate the alterations in bone mineral density and other surrogate markers for osteoporosis in obese patients with... Lees meer
Gepost op 21 mei 2021
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Treatment of bone fragility in patients with diabetes: antiresorptive versus anabolic?
Curr Opin Endocrinol Diabetes Obes. 2021 May 19.doi: 10.1097/MED.0000000000000645. Purpose of review: The pathogenesis of bone fragility in diabetes has not been fully characterized. The antifracture efficacy of... Lees meer
Gepost op 21 mei 2021
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Fractures After Denosumab Discontinuation: A Retrospective Study of 797 Cases
J Bone Miner Res. 2021 May 19. doi: 10.1002/jbmr.4335. A rebound of osteoclast activity during the 2 years after a treatment or prevention of osteoporosis with denosumab (Dmab) leads to an increased risk of... Lees meer
Gepost op 21 mei 2021
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Real-world effects and adverse events of romosozumab in Japanese osteoporotic patients: A prospective cohort study
Bone Rep. 2021 Apr 16;14:101068. Real-world data on the new anti-sclerostin antibody drug, romosozumab, remain scarce. There is a strong need to accumulate and analyze data on romosozumab treatment for such... Lees meer
Gepost op 16 mei 2021
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Bone density and quality in patients treated with direct-acting oral anticoagulants versus warfarin
Bone. 2021 May 8;150:116000. Introduction: Direct-acting oral anticoagulants (DOACs) are therapeutic alternatives to warfarin that act independently of vitamin K, thus not affecting bone matrix formation. The... Lees meer
Gepost op 13 mei 2021
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The duration of denosumab treatment and the efficacy of zoledronate to preserve bone mineral density after its discontinuation
J Clin Endocrinol Metab. 2021 May 12;dgab321. Context: Zoledronate is used to prevent bone loss following denosumab discontinuation but its efficacy differs among studies. Objective: To test if the... Lees meer
Gepost op 13 mei 2021
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Improving Bone Health by Optimizing the Anabolic Action of Wnt Inhibitor Multitargeting
JBMR Plus. 2021 May 6;5(5):e10462. Sclerostin antibody (romosozumab) was recently approved for clinical use in the United States to treat osteoporosis. We and others have explored Wnt-based combination therapy to... Lees meer
Gepost op 13 mei 2021
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Internal medicine inpatients' prevalence of misdiagnosed severe osteoporosis
Osteoporos Int. 2021 May 5. doi: 10.1007/s00198-021-05976-6. Introduction: Vertebral fractures (VFs) related to osteoporosis (OP) increase the risk of additional fractures and death. In inpatients, VFs are... Lees meer
Gepost op 07 mei 2021
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Longitudinal Analysis of Circulating Markers of Bone Turnover Across Multiple Decades in Osteoporotic Women
J Hand Surg Am. 2021 Apr 22;S0363-5023(21)00128-3. Purpose: The objective of this study was to analyze changes in serum markers of bone turnover across multiple decades in osteoporotic women compared with... Lees meer
Gepost op 26 april 2021
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Cigarette smoke-associated inflammation impairs bone remodeling through NFκB activation
J Transl Med. 2021 Apr 21;19(1):163. Background: Cigarette smoking constitutes a major lifestyle risk factor for osteoporosis and hip fracture. It is reported to impair the outcome of many clinical procedures,... Lees meer
Gepost op 23 april 2021
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Cost-effectiveness of sequential daily teriparatide/weekly alendronate compared with alendronate monotherapy for older osteoporotic women with prior vertebral fracture in Japan
Arch Osteoporos. 2021 Apr 17;16(1):72. Purpose: Teriparatide has proven efficacy in reducing osteoporotic fractures, but with substantial cost. We examined the cost-effectiveness of sequential... Lees meer
Gepost op 21 april 2021
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Persistence with oral bisphosphonates and denosumab among older adults in primary care in Ireland
Arch Osteoporos. 2021 Apr 17;16(1):71. Purpose: Gaps in pharmacological treatment for osteoporosis can reduce effectiveness. This study aimed to estimate persistence rates for oral bisphosphonates and denosumab... Lees meer
Gepost op 21 april 2021
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Long-term changes in lean mass in postmenopausal women and the effects of osteoporosis pharmacotherapy: A 10-year longitudinal study
Osteoporos Sarcopenia. 2021 Mar;7(1):30-35. Objectives: Although sarcopenia is diagnosed using appendicular lean mass (ALM), only a few long-term studies on changes in both ALM and bone mineral density (BMD)... Lees meer
Gepost op 21 april 2021
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Gepost op 05 april 2021