Osteoporose Nieuws
Wekelijks verschijnen er nieuwe onderzoek, publicaties en artikelen over osteoporose. Een selectie uit dit aanbod wordt doorgeplaatst op deze website. Klik hier voor de rss-nieuwsfeeds.
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Cost-effectiveness of 3 versus 6 years of zoledronic acid treatment before bisphosphonate holiday for women with osteoporosis
Osteoporos Int. 2021 Sep 13.doi: 10.1007/s00198-021-06010-5. Introduction: We compared the effectiveness and cost-effectiveness of cycles of 3 years versus 6 years of zoledronic acid treatment prior to 3-year... Lees meer
Gepost op 14 september 2021
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One leg standing time predicts fracture risk in older women independent of clinical risk factors and BMD
Osteoporos Int. 2021 Sep 8.doi: 10.1007/s00198-021-06039-6. Introduction: Physical function and risk of falls are important risk factors for fracture. A few previous studies have suggested that a one leg standing... Lees meer
Gepost op 12 september 2021
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Introducing the American Society for Bone and Mineral Research multistakeholder group secondary fracture prevention recommendations: Nurse practitioners play an important role
J. Am Assoc Nurse Pract. 2021 Sep 2.doi: 10.1097/JXX.0000000000000616. Sequelae after an osteoporosis-related fracture include significant morbidity and mortality. Preventing repeat fractures is an important aspect of... Lees meer
Gepost op 08 september 2021
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The effect of osteoporosis and its treatment on fracture healing a systematic review of animal and clinical studies
Bone Rep. 2021 Aug 16;15:101117.doi: 10.1016/j.bonr.2021.101117. Introduction: Osteoporosis is characterised by low bone mass and micro-architectural deterioration of bone structure. Its treatment is directed at... Lees meer
Gepost op 01 september 2021
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Diabetes increases the risk of bone fractures in patients on kidney replacement therapy: A DANISH national cohort study
Bone. 2021 Aug 27;116158. doi: 10.1016/j.bone.2021.116158. Background: Patients treated with dialysis or living with a kidney transplant (kidney replacement therapy, KRT) have an increased risk of bone... Lees meer
Gepost op 01 september 2021
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Bisphosphonate Use and Hospitalization for Hip Fractures in Women: An Observational Population-Based Study in France
Int J Environ Res Public Health. 2021 Aug 20;18(16):8780. Bisphosphonates are widely used in the treatment of women at risk of osteoporotic hip fracture; however, the overall effectiveness of bisphosphonates... Lees meer
Gepost op 29 augustus 2021
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A systematic review and meta-analysis of efficacy and safety of Romosozumab in postmenopausal osteoporosis
Osteoporos Int. 2021 Aug 25.doi: 10.1007/s00198-021-06095-y. The study was conducted to illustrate the effect of Romosozumab in postmenopausal osteoporosis patients. Romosozumab decreased the incidence of vertebral,... Lees meer
Gepost op 27 augustus 2021
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Long-term persistence with denosumab: real-world data from the Austrian Osteoporosis Clinic (AOC). A retrospective data analysis
Osteoporos Int. 2021 Aug 25.doi: 10.1007/s00198-021-06102-2. Purpose: To assess long-term persistence with denosumab in postmenopausal women with osteoporosis. Secondary purposes were the evaluation of... Lees meer
Gepost op 27 augustus 2021
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Dual Hip DXA. Is it Time to Change Standard Protocol?
J Clin Densitom. 2021 Jul 24;S1094-6950(21)00060-3. Previous studies have examined the utility of bilateral DXA hip bone mineral density (BMD) scans. While most studies demonstrate an advantage of bilateral hip... Lees meer
Gepost op 18 augustus 2021
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Implementation of a pharmacist and student pharmacist-led primary care service to identify and treat rural veterans at risk for osteoporotic fracture
J Am Pharm Assoc. 2021 Jul 21;S1544-3191(21)00312-5. Objective: To develop and implement a pharmacist and student pharmacist-led osteoporosis service to increase dual-energy x-ray absorptiometry (DXA)... Lees meer
Gepost op 18 augustus 2021
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Factors Associated With Adherence to Osteoporosis Medications Among Male Veterans
JBMR Plus. 2021 Jun 30;5(8):e10498. Risk factors for nonadherence to osteoporosis medication have been well described for cohorts of women with osteoporosis, but little is known about predictors or mediators of... Lees meer
Gepost op 12 augustus 2021
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Hip fracture predicts subsequent hip fracture: a retrospective observational study to support a call to early hip fracture prevention efforts in post-fracture patients
Osteoporos Int. 2021 Aug 11;1-10. Purpose: This large retrospective cohort study aimed to provide hip fracture data, in the context of other fractures, to help inform efforts related to hip fracture... Lees meer
Gepost op 12 augustus 2021
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Zoledronic acid and bone health in older adults with cognitive impairment
Osteoporos Int. 2021 Aug 2. doi: 10.1007/s00198-021-06063-6 Introduction: Osteoporosis has detrimental consequences for frail older adults. The effects on those with both osteoporosis and cognitive impairment... Lees meer
Gepost op 04 augustus 2021
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Predicting imminent fractures in patients with a recent fracture or starting oral bisphosphonate therapy: development and international validation of prognostic models
J Bone Miner Res. 2021 Aug 3. doi: 10.1002/jbmr.4414. The availability of anti-osteoporosis medications with rapid onset and high potency requires tools to identify patients at high imminent fracture risk (IFR). There are... Lees meer
Gepost op 04 augustus 2021
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Efficacy of romosozumab in patients with osteoporosis on maintenance hemodialysis in Japan; an observational study
J Bone Miner Metab. 2021 Jul 29. doi: 10.1007/s00774-021-01253-y. Introduction: Romosozumab reportedly increases bone mineral density (BMD) potently but might adversely affect cardiovascular disease (CVD). We... Lees meer
Gepost op 02 augustus 2021
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Is teriparatide therapy effective for medication-related osteonecrosis of the jaw? A systematic review and meta-analysis
Osteoporos Int. 2021 Jul 31.doi: 10.1007/s00198-021-06078-z. Purpose: To integrate the data published on the effect of teriparatide (TPTD) therapy on cases of medication-related osteonecrosis of the jaws (MRONJ)... Lees meer
Gepost op 02 augustus 2021
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Metabolomic biomarkers of low BMD: a systematic review
Osteoporos Int. 2021 Jul 26. doi: 10.1007/s00198-021-06037-8. Due to the metabolic nature of osteoporosis, this study was conducted to identify metabolomic studies investigating the metabolic profile of low bone mineral... Lees meer
Gepost op 28 juli 2021
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The pathophysiology of immunoporosis: innovative therapeutic targets
Inflamm Res. 2021 Aug;70(8):859-875. Background: The physiological balance between bone resorption and bone formation is now known to be mediated by a cascade of events parallel to the classic... Lees meer
Gepost op 18 juli 2021
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Fractures in untreated patients with osteoporosis in Germany: an InGef healthcare insurance database analysis
Osteoporos Int. 2021 Jul 15. doi: 10.1007/s00198-021-06051-w. Introduction: Osteoporosis is a skeletal disease that manifests as bone mineral density loss and low-trauma fractures. This database analysis... Lees meer
Gepost op 18 juli 2021
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Refracture and mortality following hospitalization for severe osteoporotic fractures: The Fractos Study
JBMR Plus. 2021 May 14;5(7):e10507. Severe osteoporotic fractures (hip, proximal humerus, pelvic, vertebral and multiple rib fractures) carry an increased risk of mortality. This retrospective cohort study in the... Lees meer
Gepost op 15 juli 2021
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Acute Phase Reactions After Intravenous Infusion of Zoledronic Acid in Japanese Patients with Osteoporosis: Sub-analyses of the Phase III ZONE Study
Calcif Tissue Int. 2021 Jul 10. doi: 10.1007/s00223-021-00884-7. In a clinical trial involving Japanese patients with osteoporosis, post hoc analyses were performed to evaluate the incidence of acute phase... Lees meer
Gepost op 13 juli 2021
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Osteoporotic fractures and subsequent fractures: imminent fracture risk from an analysis of German real-world claims data
Arch Gynecol Obstet. 2021 Sep;304(3):703-712. Purpose: In osteoporosis, prior fracture is a strong predictor of subsequent fracture. This study aimed to assess the imminent risk of subsequent fracture... Lees meer
Gepost op 13 juli 2021
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Pharmacological interventions versus placebo, no treatment or usual care for osteoporosis in people with chronic kidney disease stages 3-5D
Cochrane Database Syst Rev. 2021 Jul 7;7(7):CD013424. Background: Chronic kidney disease (CKD) is an independent risk factor for osteoporosis and is more prevalent among people with... Lees meer
Gepost op 08 juli 2021
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Bisphosphonates, Bone and Joint Pain
Curr Osteoporos Rep. 2021 Jul 3. Purpose of review: Bisphosphonates (BPs) have an established role in a number of diseases including osteoporosis, but the role of BPs for treating symptomatic conditions... Lees meer
Gepost op 04 juli 2021
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Long-term risk of subsequent major osteoporotic fracture and hip fracture in men and women: a population-based observational study with a 25-year follow-up
Osteoporos Int 2021 Jun 24. doi: 10.1007/s00198-021-06028-9. Introduction: The risk of subsequent fractures is increased following an index fracture, and declines over time. We aimed to determine... Lees meer
Gepost op 25 juni 2021
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Osteoporosis, fracture, osteoarthritis & sarcopenia: A systematic review of circulating microRNA association
Bone 2021 Jun 21;116068. Circulating microRNAs (c-miRs) show promise as biomarkers. This systematic review explores their potential association with age-related fracture/osteoporosis (OP), osteoarthritis (OA) and... Lees meer
Gepost op 25 juni 2021
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Multiple vertebral fractures after suspension of denosumab. A series of 56 cases
Int J clin Pract. 2021 Jun 19;e14550. Background: Denosumab is a monoclonal antibody approved for the treatment of postmenopausal osteoporosis. The withdrawal of denosumab produces an abrupt loss of bone... Lees meer
Gepost op 22 juni 2021
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Systematic review of major osteoporotic fracture to hip fracture incidence rate ratios worldwide: Implications to FRAX derived estimates
J Bone Miner Res. 2021 Jun 21.doi: 10.1002/jbmr.4395. The Fracture Risk Assessment Tool (FRAX) is the most widely used tool for fracture prediction. It provides 10-year probabilities for hip and major osteoporotic... Lees meer
Gepost op 22 juni 2021