Paget's disease of bone.
Best Pract Res Clin Endocrinol Metab. 2018 Oct;32(5):657-668 Authors: Appelman-Dijkstra NM, Papapoulos SE
Paget's disease of bone is a focal disorder of bone remodelling that progresses slowly and leads to changes in the shape and size of affected bones and to skeletal, articular and vascular complications. In some parts of the world it is the second most common bone disorder after osteoporosis though in recent years its prevalence and severity appear to decrease. The disease is easily diagnosed and effectively treated but its pathogenesis remains incompletely understood. PMID: 30449547 [PubMed - in process]